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publisher_rssPhys.orgAug 31, 2026

Peptides can form well-defined structures in harsh, Venus-like conditions

MIT researchers have found that short peptides can form well-defined structures in highly acidic conditions similar to those found in Venus's cloud layer. The study shows that peptides can remain stable and fold into shapes that may allow them to perform biological functions, even in the presence of 98% sulfuric acid. The researchers used nuclear magnetic resonance (NMR) spectroscopy to analyze the structures of various molecules in a solution of sulfuric acid, and found that peptides remained intact for many weeks without water, which is present in such acidic solutions. The peptides formed omega loops in the acidic environment, a shape that is occasionally found in naturally occurring proteins. The findings suggest that life may exist in environments other than Earth, such as Venus's cloud layer, and that peptides may have biological functions in such conditions.

  • The study was conducted by Mei Hong, Sara Seager, and Janusz Petkowski.
  • The researchers used NMR spectroscopy to analyze peptides in sulfuric acid.
  • The peptides remained stable for many weeks without water, which is present in such acidic solutions.
  • The peptides formed omega loops in the acidic environment, a shape that is occasionally found in naturally occurring proteins.
  • The findings suggest that life may exist in environments other than Earth, such as Venus's cloud layer, and that peptides may have biological functions in such conditions.

The study highlights the potential for life to exist in environments other than Earth, such as Venus's cloud layer, and shows that peptides may have biological functions in such conditions. The findings open up new possibilities for the search for life in the solar system and suggest that scientists should not rule out planets that do not resemble Earth in their search for life. The study also shows that peptides can form well-defined structures in acidic environments, which is an important step in understanding how life might function in such conditions. The researchers are now exploring the stability of peptide nucleic acid (PNA) in highly acidic environments and the potential for longer peptides to form similar structures.

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